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Professor Pier Lambiase

Consultant Cardiologist

(Electrophysiologist and Complex Devices)


Professor Pier Lambiase is a Consultant Cardiologist (Heart Specialist), in London specialising in the treatment of heart rhythm disorders (arrhythmias) and implants pacemakers, implantable cardioverter defibrillators (ICD’s) including subcutaneous ICDs (S-ICDs) and biventricular devices for heart failure. He has additional expertise in inherited heart rhythm problems including Long QT and Brugada Syndrome and sudden arrhythmic death syndrome (SADS) family screening.

He also specialises in the treatment of angina (chest pain), heart attack, heart failure, high blood pressure and cholesterol, and heart valve disease.

Research & Awards

Prof. Lambiase’s research is focused on the causes of cardiac arrest and the use of new technologies in treating heart rhythm disorders including pioneering the use of the subcutaneous ICD and new heart mapping technologies to improve diagnosis & guide ablation.

  • British Cardiovascular Society Michael Davies Award 2015
  • Fellow of the Heart Rhythm Society, USA, 2014
  • Fellow of the Royal College of Physicians, 2011
  • HEFCE Clinical Senior Lectureship Award, July 2006
  • British Cardiovascular Society Young Investigator Award (Clinical Science), May 2002
  • North American Society of Pacing and Electrophysiology (NASPE), Young Investigator Award-Finalist, May 2002
  • European Microcirculation Society Young Investigator Prize, Sept 2002
  • AHA Traveling Fellowship, 2001
  • Novartis AHA Scholarship, 2000
  • University College Exhibition, 1987-89

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Education and experience

Professor Pier Lambiase is a Consultant Cardiologist specialising in the treatment of heart rhythm disorders and pacemaker implantation. He graduated from Oxford University in 1992 and trained in Cardiology at St Thomas’ and Hammersmith Hospitals. Following completion of a PhD in 2002 he undertook higher specialist training in Electrophysiology and became a Consultant Cardiologist & Senior Lecturer at the Heart Hospital, UCL in 2006 and was promoted to Professor to Professor of Cardiology at University College London (UCL). He was the British Cardiac Society Young Investigator (YI) in 2002 and finalist in the North American Pacing & Electrophysiology Society (NASPE) YI competition in the same year.

Professor Lambiase conducts research into the causes and treatment of inherited rhythm disturbances at Barts Heart Centre, a state-of-the-art new facility that brings together the expertise of UCL's Heart Hospital and St Bart's London Chest Hospital. He runs a nationally-recognised SADS (Sudden Arrhythmic Death Syndrome) clinic that offers screening to at risk families and is Co-Director of cardiovascular research at Barts.

Professor Lambiase is the co-author of the Heart Rhythm UK Guidelines on genetic testing and the management of these conditions, EHRA Guidelines on SVT, HRS Guidelines on Inherited Conduction Disorders and has published over 300 peer-reviewed papers and book chapters in Cardiology. He is an Editor of the Oxford Handbook of Inherited Cardiovascular Disease and the Research Committee Chair for the British Heart Rhythm Society.

Key publications

  • Ramírez J, Duijvenboden SV, Ntalla I, Mifsud B, Warren HR, Tzanis E, Orini M, Tinker A, Lambiase PD*, Munroe PB. Thirty loci identified for heart rate response  to exercise and recovery implicate autonomic nervous system. Nat Commun. 2018 May 16;9(1):1947. doi: 10.1038/s41467-018-04148-1. (*joint senior author)
  • Nunn LM, Lopes LR, Syrris P, Murphy C, Plagnol V, Firman E, Dalageorgou C, Zorio E, Domingo D, Murday V, Findlay I, Duncan A, Carr-White G, Robert L, Bueser T, Langman C, Fynn SP, Goddard M, White A, Bundgaard H, Ferrero-Miliani L, Wheeldon N, Suvarna SK, O'Beirne A, Lowe MD, McKenna WJ, Elliott PM, Lambiase PD. Diagnostic yield of molecular autopsy in patients with sudden arrhythmic death syndrome using targeted exome sequencing. Europace. 2016 Jun;18(6):888-96. doi: 10.1093/europace/euv285. Epub 2015 Oct 25.
  • Nunn LM, Bhar-Amato J, Lowe MD, Macfarlane PW, Rogers P, McKenna WJ, Elliott PM, Lambiase PD. Prevalence of J-point elevation in sudden arrhythmic death syndrome families. J Am Coll Cardiol. 2011 Jul 12;58(3):286-90. doi: 10.1016/j.jacc.2011.03.028.
  • Boersma L, Barr C, Knops R, Theuns D, Eckardt L, Neuzil P, Scholten M, Hood M, Kuschyk J, Jones P, Duffy E, Husby M, Stein K, Lambiase PD; EFFORTLESS Investigator Group.Implant and Midterm Outcomes of the Subcutaneous Implantable Cardioverter-Defibrillator Registry: The EFFORTLESS Study. J Am Coll Cardiol. 2017 Aug 15;70(7):830-841. doi: 10.1016/j.jacc.2017.06.040
  • Graham AJ, Orini M, Zacur E, Dhillon G, Daw H, Srinivasan NT, Lane JD, Cambridge A, Garcia J, O'Reilly NJ, Whittaker-Axon S, Taggart P, Lowe M, Finlay M, Earley MJ, Chow A, Sporton S, Dhinoja M, Schilling RJ, Hunter RJ, Lambiase PD. Simultaneous Comparison of Electrocardiographic Imaging and Epicardial Contact Mapping in Structural Heart Disease. Circ Arrhythm Electrophysiol. 2019 Apr;12(4):e007120. doi: 10.1161/CIRCEP.118.007120. PubMed PMID: 30947511.   
  • Andrews CM, Srinivasan NT, Rosmini S, Bulluck H, Orini M, Jenkins S, Pantazis A, McKenna WJ, Moon JC, Lambiase PD, Rudy Y. Electrical and Structural Substrate of Arrhythmogenic Right Ventricular Cardiomyopathy Determined Using Noninvasive Electrocardiographic Imaging and Late Gadolinium Magnetic Resonance Imaging. Circ Arrhythm Electrophysiol. 2017;10(7).
  • Bhar-Amato J, Finlay M, Santos D, Orini M, Chaubey S, Vyas V, Taggart P, Grace AA, Huang CL, Ben Simon R, Tinker A, Lambiase PD. Pharmacological Modulation of Right Ventricular Endocardial-Epicardial Gradients in Brugada Syndrome. Circ Arrhythm Electrophysiol. 201Sep;11(9):e006330. doi: 10.1161/CIRCEP.118.006330. PubMed PMID: 30354290.   
  • Martin CA, Orini M, Srinivasan NT, Bhar-Amato J, Honarbakhsh S, Chow AW, Lowe MD, Ben-Simon R, Elliott PM, Taggart P, Lambiase PD. Assessment of a conduction-repolarisation metric to predict Arrhythmogenesis in right ventricular disorders. Int J Cardiol. 2018 Nov 15;271:75-80. doi: 10.1016/j.ijcard.2018.05.063. Epub 2018 May 20. PubMed PMID: 29871808
  • Lambiase PD, Ahmed AK, Ciaccio EJ, Brugada R, Lizotte E, Chaubey S, Ben-Simon R, Chow AW, Lowe MD, McKenna WJ. High-density substrate mapping in Brugada syndrome: combined role of conduction and repolarization heterogeneities in arrhythmogenesis. Circulation. 2009 Jul 14;120(2):106-17, 1-4.

Clinical interests

Professor Lambiase's main areas of expertise in Cardiology involve treating patients with palpitations, breathlessness, black-outs and severe dizzy spells. He specialises in the treatment of all arrhythmias and implants pacemakers, internal cardiac defibrillators and biventricular devices for heart failure. He performs ablation of abnormal heart rhythms: Supraventricular arrhythmias (SVT) including atrial fibrillation (AF), atrial flutter, Wolff Parkinson White Syndrome and ventricular tachycardia (VT). He treats patients with heart failure and manages rarer inherited arrhythmia syndromes including long QT Syndrome, Brugada Syndrome, Catecholiminergic Polymorphic Ventricular Tachycardia (CPVT). He performs screening of families for these inherited arrhythmia disorders in a specialist SADS (Sudden Arrhythmic Death Syndrome) clinic and treats patients with a previous cardiac arrest in whom no clear cause has been identified.